Dopamine antagonists [selection]

TerraQSAR-LOGPTM computed octanol/water partition coefficients (CLOGPs).


For other toxicity and effect values, such as mammalian (rat/mouse) intravenous LD50, mammalian (rat/mouse) oral LD50,
Daphnia magna 48-hr LC50, fish (fathead minnow) 96-hr LC50, estrogen receptor binding affinity (RBA), skin irritation potential,
use TerraQSAR-RMIV, TerraQSAR-OMAR, TerraQSAR-Daphnia, TerraQSAR-FHM, TerraQSAR-E2-RBA, or TerraQSAR-SKIN programs,


NAME CAS FORMULA MWTerraQSAR - LOGP
mezilamine 50335-55-2 C11H18ClN5S 287.82
1.02
raclopride 84225-95-6 C15H20Cl2N2O3 347.24
1.54
levosulpiride; (S)-sulpiride 23672-07-3 C15H23N3O4S 341.43
0.57
eticlopride 84226-12-0 C17H25ClN2O3 340.85
1.60
chlorprothixene-cis; CPT 113-59-7 C18H18ClNS 315.87
4.32
loxapine 1977-10-2 C18H18ClN3O 327.81
3.60
triflupromazine; fluopromazine 146-54-3 C18H19F3N2S 352.42
5.54
azaperone 1649-18-9 C18H20FN3O 313.38
3.25
berupipam 150490-85-0 C19H19BrClNO2 408.73
4.11
acepromazine 61-00-7 C19H22N2OS 326.46
4.69
romergoline 107052-56-2 C20H22N4O2 350.42
2.95
metixene; methixene 4969-02-2 C20H23NS 309.47
4.25
oxiperomide 5322-53-2 C20H23N3O2 337.42
4.25
bromerguride 83455-48-5 C20H25BrN4O 417.36
2.95
itopride 122898-67-3 C20H26N2O4 358.44
2.33
itopuride hydrochloride 122892-31-3 C20H27ClN2O4 394.90
2.60
ziprasidone 146939-27-7 C21H21ClN4OS 412.94
3.95
trifluoperazine; trifluperazine 117-89-5 C21H24F3N3S 407.50
5.03
mesoridazine 5588-33-0 C21H26N2OS2 386.58
5.83
clopenthixol-trans 982-24-1 C22H25ClN2OS 400.97
3.85
clopenthixol-cis 53772-83-1 C22H25ClN2OS 400.97
3.85
spiroxatrine 1054-88-2 C22H25N3O3 379.46
4.74
tiotixene 3313-26-6 C23H29N3O2S2 443.63
4.13
blonanserin 132810-10-7 C23H30FN3 367.51
3.28
pipotiazine 39860-99-6 C24H33N3O3S2 475.67
4.53
savoxepin 79262-46-7 C25H26N2O 370.50
2.77
butaclamol, (+) 51152-91-1 C25H31NO 361.53
4.02
isobutaclamol 58371-68-9 C25H31NO 361.53
4.35
penfluridol 26864-56-2 C28H27ClF5NO 523.97
3.78
fluspirilene 1841-19-6 C29H31F2N3O 475.58
4.65


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