Muscarinic antagonists [selection]

TerraQSAR-LOGPTM computed octanol/water partition coefficients (CLOGPs).


For other toxicity and effect values, such as mammalian (rat/mouse) intravenous LD50, mammalian (rat/mouse) oral LD50,
Daphnia magna 48-hr LC50, fish (fathead minnow) 96-hr LC50, estrogen receptor binding affinity (RBA), skin irritation potential,
use TerraQSAR-RMIV, TerraQSAR-OMAR, TerraQSAR-Daphnia, TerraQSAR-FHM, TerraQSAR-E2-RBA, or TerraQSAR-SKIN programs,


NAME CAS FORMULA MWTerraQSAR - LOGP
homatropine 87-00-3 C16H21NO3 275.35
1.83
tropicamide 1508-75-4 C17H20N2O2 284.36
3.07
cyclopentolate 512-15-2 C17H25NO3 291.39
2.06
vamicamide 132373-81-0 C18H23N3O 297.40
2.58
nuvenzepine 96487-37-5 C19H20N4O2 336.39
1.64
pirenzepine 28797-61-7 C19H23N5O2 351.41
3.25
revatropate 149926-91-0 C19H29NO4S 367.51
3.06
dicycloverine; dicyclomine 77-19-0 C19H35NO2 309.49
8.13
imidafenacin 170105-16-5 C20H21N3O 319.41
3.47
benactyzine 302-40-9 C20H25NO3 327.42
4.74
terodiline 15793-40-5 C20H27N 281.44
4.11
trihexyphenidyl 144-11-6 C20H31NO 301.47
7.64
benztropine; benzatropine 86-13-5 C21H25NO 307.44
3.85
methantheline 5818-17-7 C21H26NO3 340.44
3.76
tolterodine 124937-51-5 C22H31NO 325.50
3.94
dexetimide 21888-98-2 C23H26N2O2 362.47
3.89
solifenacin 242478-37-1 C23H26N2O2 362.47
4.73
propantheline bromide 298-50-0 C23H30BrNO3 448.41
3.89
idaverine 100927-13-7 C24H39N3O3 417.59
3.46
aclidinium bromide 320345-99-1 C26H30BrNO4S2 564.57
2.72
darifenacin; UK-88,525 133099-04-4 C27H28N2O4 444.53
3.87
zamifenacin 127308-82-1 C27H29NO3 415.53
3.62


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